Tissue Factor Antibody (YA7080)
(Synonyms: Coagulation Factor III; Tissue Factor; TF; Thromboplastin; platelet tissue factor; factor III; factor 3; F3; F-3; TFA)Tissue Factor Antibody is a non-conjugated antibody, targeting to CD142.
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Formulation:
Supplied in Phosphate-buffered solution.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Product Details
Tissue Factor Antibody is a non-conjugated antibody, targeting to CD142.
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in Phosphate-buffered solution.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Tissue Factor is an Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade
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Subcellular Localization
Membrane; Single-pass type I membrane protein; Secreted
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Expression
Tissue_specificity:Lungs, placenta and pancreas
Induction:TF expression is highly dependent upon cell type. TF can also be induced by the inflammatory mediators interleukin 1 and TNF-alpha, as well as by endotoxin, to appear on monocytes and vascular endothelial cells as a component of cellular immune response -
Isoforms & Post-Translational Modification
P13726 has 2 isomers: P13726-1: 33068 Da (predicted); P13726-2: 27145 Da (predicted).
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Subunit
Interacts with HSPE; the interaction, inhibited by heparin, promotes the generation of activated factor X and activates coagulation in the presence of activated factor VII
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SwissProt ID
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Synonyms
Coagulation Factor III; Tissue Factor; TF; Thromboplastin; platelet tissue factor; factor III; factor 3; F3; F-3; TFA
Documentation
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