1. JAK/STAT Signaling
    Protein Tyrosine Kinase/RTK
  2. EGFR
  3. BAY 2476568

BAY 2476568 

Cat. No.: HY-134877
Handling Instructions

BAY 2476568 is a potent and selective EGFR inhibitor, with IC50s of < 0.2 nM for wild-type EGFR and several mutations (EGFRR ex20insSVD, EGFRR ex20insASV, EGFRR ex20insNPG).

For research use only. We do not sell to patients.

BAY 2476568 Chemical Structure

BAY 2476568 Chemical Structure

CAS No. : 2311901-93-4

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Description

BAY 2476568 is a potent and selective EGFR inhibitor, with IC50s of < 0.2 nM for wild-type EGFR and several mutations (EGFRR ex20insSVD, EGFRR ex20insASV, EGFRR ex20insNPG)[1].

Molecular Weight

454.49

Formula

C₂₄H₂₇FN₄O₄

CAS No.
SMILES

O=C1C2=C(NC(C3=C(OCC(C)(OC)C)C=NC=C3)=C2NC4=CC=CC(F)=C4OC)CCN1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

BAY 2476568BAY2476568BAY-2476568EGFREpidermal growth factor receptorErbB-1HER1mutationscancerInhibitorinhibitorinhibit

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BAY 2476568
Cat. No.:
HY-134877
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