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EGFR-IN-140

EGFR-IN-140 (Compound 31) is the inhibitor for EGFR, that inhibits EGFR wildtype and EGFR L858R/T790M/C797S mutant with Ki of 0.95 nM and 2.1 nM, and inhibits EGFR del19/T790M/C797S in Ba/F3 with an IC50 of 56.9 nM. EGFR-IN-140 exhibits antitumor efficacy in mouse model.

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  • 分子式: C27H37FN8O2
  • 分子量:524.63
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • EGFR-IN-140 Chemical Structure
    EGFR-IN-140 構造式
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  • EGFR-IN-140 Chemical Structure
    EGFR-IN-140 Chemical Structure
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  • EGFR-IN-140