Monocalcium glycerophosphate
Based on 1 Customer Validation
Monocalcium glycerophosphate is an inhibitor of intestinal alkaline phosphatase F3, and it has anti-cavity properties. Monocalcium glycerophosphate is a source of calcium and phosphorus in total parenteral nutrition solutions, helps prevent the mineralization and development of bones from intravenous nutrition, and maintains the integrity of the intestinal epithelium.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 27214-00-2
- Formula: C3H7CaO6P
- Molecular Weight:210.14
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Monocalcium glycerophosphate (1-1000 μM, 0-24 h) protects trans-epithelial electrical resistance (TEER) in Caco-2 cells and reduces the increase in mannitol permeability rate[1].
Monocalcium glycerophosphate (0.10%, 0.25%, 0.50%) significantly decreases the level of demineralization in an in vitro bacterial flow chamber model[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Piglets[3]
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Dosage:The concentration meets the requirement of 15 mmol of Ca and 15 mmol of P per kg per day for intravenous injection in piglets; 7 days
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Administration:Jugular vein catheterization
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Result:Increased the retention of calcium and phosphorus, the mineralization of the little pigs' bones had noticeably improved, with higher calcium to lean dry weight ratios observed in the humerus and femur.
Chemical Information
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CAS No. 27214-00-2
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Appearance Solid
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Molecular Weight 210.14
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Formula C3H7CaO6P
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Color White to off-white
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SMILES
O=P([O-])([O-])OCC(O)CO.[Ca+2]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
H2O : 40 mg/mL (190.35 mM; ultrasonic and adjust pH to 3 with 1 M HCl)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Handling Instructions (2659 KB)
References
[1]. Datta P, et al. Calcium glycerophosphate preserves transepithelial integrity in the Caco-2 model of intestinal transport. World J Gastroenterol. 2015;21(30):9055-9066. [Content Brief]
[3]. Draper HH, et al. Calcium glycerophosphate as a source of calcium and phosphorus in total parenteral nutrition solutions. JPEN J Parenter Enteral Nutr. 1991;15(2):176-180. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.7587 mL | 23.7937 mL | 47.5873 mL | 118.9683 mL |
| 5 mM | 0.9517 mL | 4.7587 mL | 9.5175 mL | 23.7937 mL | |
| 10 mM | 0.4759 mL | 2.3794 mL | 4.7587 mL | 11.8968 mL | |
| 15 mM | 0.3172 mL | 1.5862 mL | 3.1725 mL | 7.9312 mL | |
| 20 mM | 0.2379 mL | 1.1897 mL | 2.3794 mL | 5.9484 mL | |
| 25 mM | 0.1903 mL | 0.9517 mL | 1.9035 mL | 4.7587 mL | |
| 30 mM | 0.1586 mL | 0.7931 mL | 1.5862 mL | 3.9656 mL | |
| 40 mM | 0.1190 mL | 0.5948 mL | 1.1897 mL | 2.9742 mL | |
| 50 mM | 0.0952 mL | 0.4759 mL | 0.9517 mL | 2.3794 mL | |
| 60 mM | 0.0793 mL | 0.3966 mL | 0.7931 mL | 1.9828 mL | |
| 80 mM | 0.0595 mL | 0.2974 mL | 0.5948 mL | 1.4871 mL | |
| 100 mM | 0.0476 mL | 0.2379 mL | 0.4759 mL | 1.1897 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Monocalcium glycerophosphate Related Classifications
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