TP53I3 (PIG3) Antibody (YA7898)
(Synonyms: PIG3)TP53I3 (PIG3) Antibody (YA7898) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TP53I3 (PIG3).
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-4000 | 1:150-500 |
Product Details
TP53I3 (PIG3) Antibody (YA7898) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TP53I3 (PIG3).
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 35.4 kDa
Full length human recombinant protein of human TP53I3 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TP53I3 catalyzes the NADPH-dependent reduction of quinones. Exhibits a low enzymatic activity with beta-naphthoquinones, with a strong preference for the ortho-quinone isomer (1,2-beta-naphthoquinone) over the para isomer (1,4-beta-naphthoquinone). Also displays a low reductase activity for non-quinone compounds such as diamine and 2,6-dichloroindophenol (in vitro). Involved in the generation of reactive oxygen species (ROS)[1].
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Expression
Induction: Isoform 1 and isoform 2 are both activated by p53/TP53, doxorubicin, etoposide and ionizing radiation. Isoform 2 is highly activated by UV radiation
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Isoforms & Post-Translational Modification
Q53FA7 has two isomers: Q53FA7-1: 35536 Da (predicted); Q53FA7-2: 25402 Da (predicted).
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Subunit
Homodimer
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SwissProt ID
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Synonyms
PIG3
Documentation
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