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Transferrin Receptor 2 Antibody (YA1845)

(Synonyms: HFE3; TfR2; TFRC2)
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Transferrin Receptor 2 Antibody (YA1845) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transferrin Receptor 2.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IHC-P

  • Reactivity :

    Human

  • Formulation:

    Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

  • Conjugation:
    Non-conjugated
  • Transferrin Receptor 2 Antibody (YA1845) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
Dilution Ratio 1:1000-1:2000 1:50-1:100

Product Details

Description

Transferrin Receptor 2 Antibody (YA1845) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transferrin Receptor 2.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 100 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 89 kDa
Species Reactivity Database

Entrez Gene: 7036 Human

SwissProt: Q9UP52 Human

Immunogen

A synthesized peptide derived from human Transferrin Receptor 2 aa150-300/801.

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Transferrin Receptor 2 mediates cellular uptake of transferrin-bound iron in a non-iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation

  • Subcellular Localization

    Cell membrane; Single-pass type II membrane protein; Cytoplasm

  • Expression


    Tissue_specificity:Predominantly expressed in liver. While the alpha form is also expressed in spleen, lung, muscle, prostate and peripheral blood mononuclear cells, the beta form is expressed in all tissues tested, albeit weakly

  • Isoforms & Post-Translational Modification

    Q9UP52 has 3 isomers: Q9UP52-1: 88755 Da (predicted); Q9UP52-2: 69618 Da (predicted); Q9UP52-3: 86012 Da (predicted).

  • Subunit

    Homodimer

  • SwissProt ID

    Q9UP52

  • Gene ID
    7036 [NCBI]
  • Synonyms

    HFE3; TfR2; TFRC2

  • Research Field

    Cardiovascular

Transferrin Receptor 2 Antibody (YA1845) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • Transferrin Receptor 2 Antibody (YA1845) Product Image