TRIP13 Antibody (YA7779)(PBS only)
(Synonyms: 16E1BP)TRIP13 Antibody (YA7779) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TRIP13.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-2000 | 1:2000-2500 |
Product Details
TRIP13 Antibody (YA7779) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TRIP13.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
Human recombinant protein fragment corresponding to amino acids 31-148 of human TRIP13 produced in E.coli.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TRIP13 plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes. Plays a role in mitotic spindle assembly checkpoint (SAC) activation[1].
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Isoforms & Post-Translational Modification
Q15645 has two isomers: Q15645-1: 48551 Da (predicted); Q15645-2: 22084 Da (predicted).
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Subunit
Specifically interacts with the ligand binding domain of the thyroid receptor (TR)
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SwissProt ID
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Synonyms
16E1BP
Documentation
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