TRIP13 Antibody (YA7779)(PBS only)

Cat. No.: HY-P88095A: Data Sheet User Guide for Antibodies
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TRIP13 Antibody (YA7779) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TRIP13.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TRIP13 Antibody (YA7779) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to TRIP13.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q15645

Immunogen

Human recombinant protein fragment corresponding to amino acids 31-148 of human TRIP13 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:2000-2500

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). Plays a role in mitotic spindle assembly checkpoint (SAC) activation (PubMed:28553959)

Isoforms & Post-Translational Modification：Q15645 has two isomers: Q15645-1: 48551 Da (predicted); Q15645-2: 22084 Da (predicted).

Subunit：Specifically interacts with the ligand binding domain of the thyroid receptor (TR)

Synonyms

16E1BP

Documentation

User Guide for Antibodies (1077 KB)