UBE3B Antibody (YA8643)
(Synonyms: BPIDS)UBE3B Antibody (YA8643) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to UBE3B.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:250-500 |
Product Details
UBE3B Antibody (YA8643) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to UBE3B.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 122.9 kDa
Human recombinant protein fragment corresponding to amino acids 768-1068 of human UBE3B produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
UBE3B is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates BCKDK and targets it for degradation, thereby regulating various metabolic processes. Involved in the positive regulation of neurite branching in hippocampal neurons and the control of neuronal spine number and morphology, through the ubiquitination of PPP3CC
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Subcellular Localization
Postsynaptic density
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Expression
Tissue_Specificity: Widely expressed -
Isoforms & Post-Translational Modification
Q7Z3V4 has three isomers: Q7Z3V4-1: 123098 Da (predicted); Q7Z3V4-2: 82097 Da (predicted); Q7Z3V4-3: 28934 Da (predicted).
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SwissProt ID
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Synonyms
BPIDS
Documentation
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