UBE3B Antibody (YA8643)

製品番号: HY-P88959: データシート User Guide for Antibodies
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UBE3B Antibody (YA8643) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to UBE3B.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

UBE3B Antibody (YA8643) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to UBE3B.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 122.9 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q7Z3V4

Immunogen

Human recombinant protein fragment corresponding to amino acids 768-1068 of human UBE3B produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:250-500

Sensitivity	Endogenous	純度	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Ubiquitinates BCKDK and targets it for degradation, thereby regulating various metabolic processes (By similarity). Involved in the positive regulation of neurite branching in hippocampal neurons and the control of neuronal spine number and morphology, through the ubiquitination of PPP3CC (By similarity)

Subcellular Localization：Postsynaptic density

Expression：
Tissue_Specificity: Widely expressed

Isoforms & Post-Translational Modification：Q7Z3V4 has three isomers: Q7Z3V4-1: 123098 Da (predicted); Q7Z3V4-2: 82097 Da (predicted); Q7Z3V4-3: 28934 Da (predicted).

Synonyms

BPIDS

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/mcf7-cell.html [Content Brief]