USP32 Antibody
(Synonyms: USP10, USP32, Ubiquitin carboxyl-terminal hydrolase 32, Deubiquitinating enzyme 32, Renal carcinoma antigen NY-REN-60, Ubiquitin thioesterase 32, Ubiquitin-specific-processing protease 32)USP32 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to USP32.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P
-
Reactivity :
Human, Mouse, Rat
-
Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
-
Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
USP32 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to USP32.
-
Host Rabbit
-
Clonality Polyclonal
-
Species ReactivityHuman, Mouse, Rat
-
Observed Molecular WeightObserved band size: 181 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 181 kDa
Synthetic peptide corresponding to the center region of human USP32.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
USP32 is a Deubiquitinase that can remove conjugated ubiquitin from target proteins, such as RAB7A and LAMTOR1. Acts as a positive regulator of the mTORC1 signaling by mediating deubiquitination of LAMTOR1, thereby promoting the association between LAMTOR1 and the lysosomal V-ATPase complex and subsequent activation of the mTORC1 complex[1].
-
Subcellular Localization
Golgi apparatus membrane
-
Isoforms & Post-Translational Modification
USP32 has 2 isoforms, Q8NFA0-1: amino acid length is 1604, molecular weight is 181656 Da (predicted); Q8NFA0-2: amino acid length is 390, molecular weight is 44703 Da (predicted).USP32 存在 2 个异构体,Q8NFA0-1:氨基酸个数为 1604 个,分子量为 181656 Da (预测);Q8NFA0-2:氨基酸个数为 390 个,分子量为 44703 Da (预测)。
-
SwissProt ID
-
Synonyms
USP10, USP32, Ubiquitin carboxyl-terminal hydrolase 32, Deubiquitinating enzyme 32, Renal carcinoma antigen NY-REN-60, Ubiquitin thioesterase 32, Ubiquitin-specific-processing protease 32
Documentation