WASF3 Antibody
(Synonyms: KIAA0900, SCAR3, WAVE3, WASF3, Actin-binding protein WASF3, Protein WAVE-3, Verprolin homology domain-containing protein 3, Wiskott-Aldrich syndrome protein family member 3, WASP family protein member 3)WASF3 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to WASF3.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 |
Product Details
WASF3 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to WASF3.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 55 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 55 kDa
Synthetic peptide corresponding to the center region of human WASF3.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
WASF3 is a Downstream effector molecules involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Required for regulation of cell morphology and cytoskeletal organization[1].
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Subcellular Localization
Cytoplasm, cytoskeleton
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Expression
Tissue_Specificity: Expressed in ovary and brain. -
Isoforms & Post-Translational Modification
WASF3 has 2 isoforms, Q9UPY6-1: amino acid length is 502, molecular weight is 55293 Da (predicted); Q9UPY6-2: amino acid length is 499, molecular weight is 55007 Da (predicted).ABL1 对其的磷酸化可促进板状伪足的形成和细胞迁移WASF3 存在 2 个异构体，Q9UPY6-1：氨基酸个数为 502 个，分子量为 55293 Da (预测)；Q9UPY6-2：氨基酸个数为 499 个，分子量为 55007 Da (预测)。Phosphorylation by ABL1 promotes lamellipodia formation and cell migration
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Subunit
Binds actin and the Arp2/3 complex
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SwissProt ID
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Synonyms
KIAA0900, SCAR3, WAVE3, WASF3, Actin-binding protein WASF3, Protein WAVE-3, Verprolin homology domain-containing protein 3, Wiskott-Aldrich syndrome protein family member 3, WASP family protein member 3
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