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  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. WDR74 Antibody (YA8683)(PBS only)

WDR74 Antibody (YA8683)(PBS only)

Cat. No.: HY-P88999A
User Guide for Antibodies Technical Support

WDR74 Antibody (YA8683) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to WDR74.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

WDR74 Antibody (YA8683) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to WDR74.
Host

Mouse
Molecular Weight

Predicted band size: 42.3 kDa
Species Reactivity
Human, Dog, Rat, Monkey, Mouse
SwissProt ID
Immunogen

Human recombinant protein fragment corresponding to amino acids 114-385 of human WDR74 produced in E.coli.
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:150-500
Purity Affinity purified Conjugation Non-conjugated
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit (PubMed:26456651). Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (PubMed:29107693). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development (By similarity)
Subcellular Localization：Nucleus, nucleolus,Nucleus
Isoforms & Post-Translational Modification：Q6RFH5 has two isomers: Q6RFH5-1: 42441 Da (predicted); Q6RFH5-2: 40208 Da (predicted).
Subunit：Isoform 1 interacts (through WDR repeats) with NVL; the interaction is independent of RNA or pre-60S ribosome particles
Synonyms
FLJ10439; FLJ21730
Documentation
User Guide for Antibodies (1077 KB)

WDR74 Antibody (YA8683)(PBS only) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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WDR74 Antibody (YA8683)(PBS only)
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