2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. ZEB2 Antibody (YA7746)(PBS only)

ZEB2 Antibody (YA7746)(PBS only)

Cat. No.: HY-P88062A
User Guide for Antibodies Technical Support

ZEB2 Antibody (YA7746) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ZEB2.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

ZEB2 Antibody (YA7746) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ZEB2.
Host

Mouse
Species Reactivity
Human, Mouse, Rat
SwissProt ID
Immunogen

Human recombinant protein fragment corresponding to amino acids 1-350 of human ZEB2 produced in E.coli.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:2000-3000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:150-500
Purity Affinity purified Conjugation Non-conjugated
Isotype IgG1  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Transcriptional inhibitor that binds to DNA sequence 5'-CACCT-3' in different promoters (PubMed:16061479, PubMed:20516212). Represses transcription of E-cadherin (PubMed:16061479). Represses expression of MEOX2 (PubMed:20516212)
Subcellular Localization：Nucleus,Chromosome
Expression：Induction: Down-regulated by microRNA-221 (miR-221)
Isoforms & Post-Translational Modification：O60315 has two isomers: O60315-1: 136447 Da (predicted); O60315-2: 133806 Da (predicted).
Sumoylation on Lys-391 and Lys-866 is promoted by the E3 SUMO-protein ligase CBX4, and impairs interaction with CTBP1 and transcription repression activity
Subunit：Binds activated SMAD1, activated SMAD2 and activated SMAD3; binding with SMAD4 is not detected (By similarity)
Synonyms
HSPC082; SIP-1; SIP1; SMADIP1; ZFHX1B
Documentation
User Guide for Antibodies (1077 KB)

ZEB2 Antibody (YA7746)(PBS only) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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ZEB2 Antibody (YA7746)(PBS only)
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