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Cat. No.: HY-106501A

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Asocainol hydrochloride

(Synonyms: Goe 4704 hydrochloride)

Asocainol hydrochloride (Goe 4704 hydrochloride) is an antiarrhythmic agent. Asocainol hydrochloride reduces the maximum rate of action potential rise and action potential amplitude. Asocainol hydrochloride is applicable for the research of arrhythmias.

For research use only. We do not sell to patients.

CAS No.: 91574-89-9
Formula: C₂₇H₃₂ClNO₃
Molecular Weight:454.00

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Asocainol hydrochloride Chemical Structure

CAS No.: 91574-89-9

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Biological Activity
- Description
- In Vitro
Chemical Information
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Biological Activity

Description

In Vitro

Hydrochloride of Asocainol (3-30 μM) exerts the following effects on papillary muscles (32℃; K_e⁺ 5.9 mmol/L; stimulation frequency 0.5 Hz): no change in resting potential, concentration-dependent reduction in the maximum upstroke velocity of action potential (-16% to -67%), decrease in action potential amplitude (-4% to -16%), and shortening of action potential duration at 50% repolarization (-18% to -43%)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 91574-89-9
Molecular Weight 454.00
Formula C₂₇H₃₂ClNO₃
SMILES

OC1=C(C=CC2=C1C3=CC(OC)=CC=C3CCN(C(CCC4=CC=CC=C4)C2)C)OC.Cl
Synonyms

Goe 4704 hydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Langenfeld H, et al. Electrophysiological profile of the antiarrhythmic compound asocainol studied on perfused guinea-pig hearts and on isolated cardiac preparations. Naunyn Schmiedebergs Arch Pharmacol. 1984;326(2):155-162. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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