[Asp371]-Tyrosinase (369-377), human
Based on 1 Customer Validation
Tyrosinase 369-377, human is a HLA-A2.1-restricted epitope derived from tyrosinase, has been used to develop tumor-targeted vaccines with mixed efficacy.
For research use only. We do not sell to patients.
- Purity: 99.66%
- CAS No.: 168650-46-2
- Formula: C42H66N10O16S2
- Molecular Weight:1031.16
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
![[Asp371]-Tyrosinase (369-377), human Chemical Structure](https://file.medchemexpress.com/product_pic/hy-p1919.gif "Click to View [Asp371]-Tyrosinase (369-377), human Chemical Structure")
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 168650-46-2
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Appearance Solid
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Molecular Weight 1031.16
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Formula C42H66N10O16S2
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Color White to off-white
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Sequence
Tyr-Met-Asp-Gly-Thr-Met-Ser-Gln-Val
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Sequence Shortening
YMDGTMSQV
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 50 mg/mL (48.49 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Guillaume B, et al. Analysis of the processing of seven human tumor antigens by intermediate proteasomes. J Immunol. 2012 Oct 1;189(7):3538-47. [Content Brief]
[2]. Mitchell MS, et al. Phase I trial of adoptive immunotherapy with cytolytic T lymphocytes immunized against a tyrosinase epitope. J Clin Oncol. 2002 Feb 15;20(4):1075-86. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9698 mL | 4.8489 mL | 9.6978 mL | 24.2445 mL |
| 5 mM | 0.1940 mL | 0.9698 mL | 1.9396 mL | 4.8489 mL | |
| 10 mM | 0.0970 mL | 0.4849 mL | 0.9698 mL | 2.4245 mL | |
| 15 mM | 0.0647 mL | 0.3233 mL | 0.6465 mL | 1.6163 mL | |
| 20 mM | 0.0485 mL | 0.2424 mL | 0.4849 mL | 1.2122 mL | |
| 25 mM | 0.0388 mL | 0.1940 mL | 0.3879 mL | 0.9698 mL | |
| 30 mM | 0.0323 mL | 0.1616 mL | 0.3233 mL | 0.8082 mL | |
| 40 mM | 0.0242 mL | 0.1212 mL | 0.2424 mL | 0.6061 mL |
[Asp371]-Tyrosinase (369-377), human Related Classifications
HY-P1919 Related Classifications
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