L-162537
L-162537 is a competitive human angiotensin II receptor 1 (AT1) and receptor 2 (AT2) antagonist with an IC50=1.7 nM for AT1. L-162537 inhibits Ang II-mediated vasoconstriction, blood pressure elevation and related pathological signaling pathways. L-162537 is promising for research of angiotensin II-related cardiovascular diseases such as hypertension.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 167027-99-8
- Formel: C38H32N8O2
- Molecular Weight:632.71
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Alle Angiotensin Receptor Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
|
AT1 Receptor 1.7 nM (IC50) |
AT2 Receptor |
Chemical Information
-
CAS. Nr. 167027-99-8
-
Molecular Weight 632.71
-
Formel C38H32N8O2
-
SMILES
CCCC1=NC2=C(C(N1CC3=CC=C(C4=C(C5=NNN=N5)C=CC=C4)C=C3)=O)C=C(N(CC6=CN=CC=C6)C(C7=CC=CC=C7)=O)C=C2
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)