Plafibride
Plafibride (ITA 104) is an orally active hypolipemic, platelet aggregation inhibitor.
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- CAS. Nr.: 63394-05-8
- Formel: C16H22ClN3O4
- Molecular Weight:355.82
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Plafibride has low toxicity, with LD50s of about 4000 mg/kg (p.o.) in rat, mouse and hamster[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Rabbit[1]
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Dosage:100 mg/kg
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Administration:Oral administration (p.o.)
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Result:Induced platelet aggregation.
Chemical Information
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CAS. Nr. 63394-05-8
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Molecular Weight 355.82
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Formel C16H22ClN3O4
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SMILES
O=C(NCN1CCOCC1)NC(C(C)(C)OC2=CC=C(Cl)C=C2)=O
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Synonyms
ITA 104
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. L Bruseghini, et al. Platelet antiaggregant activity of plafibride ex vivo in rat, dog and rabbit. Arzneimittelforschung. 1981;31(10a):1790-5. [Content Brief]
[2]. J Zapatero, et al. Toxicological studies of plafibride. Part 1: Acute toxicity and its determination after several administrations of plafibride. Arzneimittelforschung. 1981;31(10a):1816-9. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Plafibride Related Classifications
HY-106580 Related Classifications
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