AZD9496-O-C3-O-C3-O-C-acid
AZD9496-O-C3-O-C3-O-C-acid is a Target Protein Ligand-Linker Conjugate that incorporates a ligand for ERα (HY-12870) and a PROTAC linker, which recruits E3 ligases. AZD9496-O-C3-O-C3-O-C-acid can be used for synthesis of PROTAC AZ'6421 (HY-135312).
For research use only. We do not sell to patients.
- CAS No.: 2361117-48-6
- Formula: C30H37F3N2O5
- Molecular Weight:562.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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ERα |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2361117-48-6
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Molecular Weight 562.62
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Formula C30H37F3N2O5
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SMILES
CC(C)(F)CN1[C@H](C2=C(C=C(C=C2F)OCCCOCCCOCC(O)=O)F)C3=C(C[C@H]1C)C4=CC=CC=C4N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)