Boc-3,3'-biazetidine hemioxalate
Based on 1 Customer Validation
Boc-3,3'-biazetidine (hemioxalate) is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- Purity: ≥98.0%
- CAS No.: 2059937-79-8
- Formula: C11H20N2O2·1/2C2H2O4
- Molecular Weight:257.31
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E524 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2059937-79-8
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Appearance Solid
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Molecular Weight 257.31
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Formula C11H20N2O2·1/2C2H2O4
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SMILES
O=C(C(O)=O)O.O=C(N1CC(C2CNC2)C1)OC(C)(C)C.[1/2]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : 10 mg/mL (38.86 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (247 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8864 mL | 19.4318 mL | 38.8636 mL | 97.1591 mL |
| 5 mM | 0.7773 mL | 3.8864 mL | 7.7727 mL | 19.4318 mL | |
| 10 mM | 0.3886 mL | 1.9432 mL | 3.8864 mL | 9.7159 mL | |
| 15 mM | 0.2591 mL | 1.2955 mL | 2.5909 mL | 6.4773 mL | |
| 20 mM | 0.1943 mL | 0.9716 mL | 1.9432 mL | 4.8580 mL | |
| 25 mM | 0.1555 mL | 0.7773 mL | 1.5545 mL | 3.8864 mL | |
| 30 mM | 0.1295 mL | 0.6477 mL | 1.2955 mL | 3.2386 mL |
Boc-3,3'-biazetidine hemioxalate Related Classifications
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