Bradykinin B1 receptor antagonist 1
Bradykinin B1 receptor antagonist 1 (compound 6B) is a potent and cross the blood-brain barrier bradykinin B1 antagonist. Bradykinin B1 receptor antagonist 1 has the potential for the research of pain.
For research use only. We do not sell to patients.
- CAS No.: 578727-81-8
- Formula: C22H19F5N2O4
- Molecular Weight:470.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Bradykinin Receptor Isoforms
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Biological Activity
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
1.9 nM
Compound: 12b-(R)
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Activity at human bradykinin B1 receptor assessed as inhibition of Des-arg kallidin-induced increase of cytosolic calcium in CHO cells by FLIPR
Activity at human bradykinin B1 receptor assessed as inhibition of Des-arg kallidin-induced increase of cytosolic calcium in CHO cells by FLIPR
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[PMID: 17228869] |
Chemical Information
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CAS No. 578727-81-8
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Molecular Weight 470.39
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Formula C22H19F5N2O4
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SMILES
C[C@H](C1=C(C=C(C2=C(C(F)=CC=C2)C(OC)=O)C=C1)F)NC(C3(CC3)NC(C(F)(F)F)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bradykinin B1 receptor antagonist 1 Related Classifications
HY-158262 Related Classifications
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