HDAC-IN-44
HDAC-IN-44 is a HDAC inhibitor with the IC50 value of 61.2 nM. HDAC-IN-44 shows high anticancer activity towards multiple cancer cell lines.
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- CAS No.: 2414921-46-1
- Formule: C26H27BrN4O4
- Masse moléculaire:539.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
HDAC-IN-44 (20 µg/mL; 24 h) treatment shows inhibitory effects on acute lymphoblastic leukemia (Molt 4 cells), T-cell lymphoblastic lymphoma (Sup-T1 cells), chronic myelogenous leukemia (K562 cells), gastric adenocarcinoma (AGS), prostate cancer (PC3 and LNCaP cells) and breast cancer (T47D cells) [1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Molt 4, Sup-T1, K562, AGS, PC-3, LNCaP, T47D cells[1]
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Concentration:20 µg/mL
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Incubation Time:24 hours
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Result:Exhibited IC50 values of 11, 9.1, 16.3, 7.1, 13.4, 32.7 and 9.2 μM in Molt 4, Sup-T1, K562, AGS, PC-3, LNCaP, T47D cells, respectively[1].
Chemical Information
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CAS No. 2414921-46-1
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Masse moléculaire 539.42
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Formule C26H27BrN4O4
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SMILES
O=C(NO)CCCCCN(C1)C([C@]2([H])CC3=C([C@H](C4=CC=C(Br)C=C4)N2C1=O)NC5=C3C=CC=C5)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HDAC-IN-44 Related Classifications
HY-150500 Related Classifications
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