1029737-28-7
Chemical Structure
G194-0712
- CAS No.: 1029737-28-7
- Formula:C20H20ClN3O
- Molecular Weight:353.85
InChIKey: YRICWULKTUDALL-UHFFFAOYSA-N
SMILES: CC(C1=CC=C(C=C1)N2C=CN=C(C2=O)NCC3=CC=CC=C3Cl)C
Biological Activity: G194-0712 is a selective histone deacetylase 5 (HDAC5) activator with an EC50 of 7.96 μM and a Kd of 2.53 μM. G194-0712 restores ACTN4-K417 deacetylation and nuclear import, and increases CSTA expression. G194-0712 accelerates wound closure in chronic wound models, reducing wound area and epithelial gap. G194-0712 can be used for the research of chronic skin wounds, such as diabetic wounds, ischemic wounds, radiation injury wounds[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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G194-0712 | 99.82% | G194-0712 is a selective histone deacetylase 5 (HDAC5) activator with an EC50 of 7.96 μM and a Kd of 2.53 μM. G194-0712 restores ACTN4-K417 deacetylation and nuclear import, and increases CSTA expression. G194-0712 accelerates wound closure in chronic wound models, reducing wound area and epithelial gap. G194-0712 can be used for the research of chronic skin wounds, such as diabetic wounds, ischemic wounds, radiation injury wounds. | ||||||||||||||||||||
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Keywords
