1043854-13-2
1043854-13-2
Chemical Structure
J14
- CAS No.: 1043854-13-2
- Formula:C28H25ClN4O2S
- Molecular Weight:517.04
IUPAC Name: 4-(((4-(4-(2-chlorophenyl)piperazin-1-yl)-6-phenylpyrimidin-2-yl)thio)methyl)benzoic acid
InChIKey: RSHUJZXWKLIBRE-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=C(CSC2=NC(C3=CC=CC=C3)=CC(N4CCN(C5=CC=CC=C5Cl)CC4)=N2)C=C1
Biological Activity: J14 is a reversible sulfiredoxin inhibitor with an IC50 of 8.1 μM. J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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J14 | 99.91% | J14 is a reversible sulfiredoxin inhibitor with an IC50 of 8.1 μM. J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin, leading to cytotoxicity and cancer cell death. | ||||||||||||||||||||
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References
Keywords
