105277-43-8
105277-43-8
Chemical Structure
PD 119819
- CAS No.: 105277-43-8
- Formula:C21H25Cl2N3O3
- Molecular Weight:438.35
IUPAC Name: 7-(3-(4-(pyridin-2-yl)piperazin-1-yl)propoxy)-4H-chromen-4-one dihydrochloride
InChIKey: QFSMSXQRZMHQGY-UHFFFAOYSA-N
SMILES: O=C1C=COC2=CC(OCCCN3CCN(CC3)C4=NC=CC=C4)=CC=C12.[H]Cl.[H]Cl
Biological Activity: PD 119819 is a highly selective benzopyran-4-one brain dopamine autoreceptor agonist. PD 119819, a heterocyclic piperazine, inhibits spontaneous locomotor activity and brain dopamine synthesis[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
PD 119819 | PD 119819 is a highly selective benzopyran-4-one brain dopamine autoreceptor agonist. PD 119819, a heterocyclic piperazine, inhibits spontaneous locomotor activity and brain dopamine synthesis. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Macallum GE, et al. Renal and hepatic toxicity of a benzopyran-4-one in the Cynomolgus monkey. Toxicology. 1989;59(1):97-108. [Content Brief]
- [2]. Jaen JC, et al. Dopamine autoreceptor agonists as potential antipsychotics. 2. (Aminoalkoxy)-4H-1-benzopyran-4-ones. J Med Chem. 1991;34(1):248-256. [Content Brief]
Keywords
