1061605-21-7

Thalidomide-O-COOH Chemical Structure
1061605-21-7

Chemical Structure

Thalidomide-O-COOH

Synonym(s): Cereblon ligand 3; E3 ligase Ligand 3

  • CAS No.: 1061605-21-7
  • Formula:C15H12N2O7
  • Molecular Weight:332.27

IUPAC Name: 2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetic acid

InChIKey: ZVWIXIGBWIEDFO-UHFFFAOYSA-N

SMILES: O=C(N(C(CCC1=O)C(N1)=O)C2=O)C(C2=CC=C3)=C3OCC(O)=O

Biological Activity: Thalidomide-O-COOH (Cereblon ligand 3) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs[1].

Cat. No. Product Name Purity Description Pricing
HY-103597
Thalidomide-O-COOH 99.45% Thalidomide-O-COOH (Cereblon ligand 3) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs.
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HY-103597R
Thalidomide-O-COOH (Standard) ≥98% Thalidomide-O-COOH (Standard) is the analytical standard of Thalidomide-O-COOH (HY-103597). This product is intended for research and analytical applications. Thalidomide-O-COOH (Cereblon ligand 3) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs.
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