1135278-54-4
Chemical Structure
CGP 78608 hydrochloride
- CAS No.: 1135278-54-4
- Formula:C11H14BrClN3O5P
- Molecular Weight:414.58
IUPAC Name: (S)-(1-(((7-bromo-2,3-dioxo-1,2,3,4-tetrahydroquinoxalin-5-yl)methyl)amino)ethyl)phosphonic acid hydrochloride
InChIKey: MZQQZBPMRPDKTB-JEDNCBNOSA-N
SMILES: OP(O)([C@H](NCC1=CC(Br)=CC(NC2=O)=C1NC2=O)C)=O.[H]Cl
Biological Activity: CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor, with an IC50 of 6 nM. CGP 78608 hydrochloride acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC50 in the low nM range (26.3 nM). Anticonvulsant activity[1][2].
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CGP 78608 hydrochloride | 99.56% | CGP 78608 hydrochloride is a highly potent and selective antagonist at the glycine-binding site of the NMDA receptor, with an IC50 of 6 nM. CGP 78608 hydrochloride acts as a potentiator of GluN1/GluN3A-mediated glycine currents, with an estimated EC50 in the low nM range (26.3 nM). Anticonvulsant activity. | ||||||||||||||||||||
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Keywords
