1139875-74-3
1139875-74-3
Chemical Structure
GSK-3β inhibitor 8
- CAS No.: 1139875-74-3
- Formula:C20H20ClN5OS
- Molecular Weight:413.92
IUPAC Name: (2-chloro-4-((4-(thiophen-2-yl)pyrimidin-2-yl)amino)phenyl)(4-methylpiperazin-1-yl)methanone
InChIKey: CLDIUVXCUVQLGD-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(NC2=NC=CC(C3=CC=CS3)=N2)C=C1Cl)N4CCN(C)CC4
Biological Activity: GSK-3β inhibitor 8, a thiophenacil derivative, is an effective and selective inhibitor of GSK-3β (IC50=64 nM). GSK-3β inhibitor 8 negatively regulated Wnt signaling pathway and stimulated β cell proliferation[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK-3β inhibitor 8 | 98.16% | GSK-3β inhibitor 8, a thiophenacil derivative, is an effective and selective inhibitor of GSK-3β (IC50=64 nM). GSK-3β inhibitor 8 negatively regulated Wnt signaling pathway and stimulated β cell proliferation. | ||||||||||||||||||||
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References
Keywords
