1144114-27-1
1144114-27-1
Chemical Structure
POP-3MB
- CAS No.: 1144114-27-1
- Formula:C38H39NO4S
- Molecular Weight:605.79
InChIKey: AHJGURHCLOZLFH-NBTOIDQYSA-N
SMILES: O=C(N[C@@H](CSC/C=C(C/C=C(C)/C)/CCC1=CC=C(C2=CC=CC=C2)C=C1)C(O)=O)C(C=CC=C3)=C3OC4=CC=CC=C4
Biological Activity: POP-3MB (compound 1b) is an ICMT inhibitor (IC50: 2.5 μM). POP-3MB changes the subcellular localization of K-Ras and inhibits Ras activation. POP-3MB also inhibits Erk phosphorylation[1].
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POP-3MB | POP-3MB (compound 1b) is an ICMT inhibitor (IC50: 2.5 μM). POP-3MB changes the subcellular localization of K-Ras and inhibits Ras activation. POP-3MB also inhibits Erk phosphorylation. | |||||||||||||||||||||
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References
Keywords
