115622-58-7
Chemical Structure
Ro 23-9424
- CAS No.: 115622-58-7
- Formula:C31H31F3N8O8S2
- Molecular Weight:764.75
IUPAC Name: (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((6,8-difluoro-1-(2-fluoroethyl)-7-(4-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carbonyl)oxy)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
InChIKey: IKYGJSBKPPIKJK-JDKVAZDPSA-N
SMILES: O=C(C(N12)=C(COC(C3=CN(CCF)C4=C(C=C(F)C(N5CCN(C)CC5)=C4F)C3=O)=O)CS[C@]2([H])[C@H](NC(/C(C6=CSC(N)=N6)=N\OC)=O)C1=O)O
Biological Activity: Ro 23-9424 is a broad-spectrum cephalosporin composed of a cephalosporin and a quinolone moiety. Ro 23-9424 shows antimicrobial activity in vivo and in vitro[1][2][3].
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Ro 23-9424 | Ro 23-9424 is a broad-spectrum cephalosporin composed of a cephalosporin and a quinolone moiety. Ro 23-9424 shows antimicrobial activity in vivo and in vitro. | |||||||||||||||||||||
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- [1]. Pfaller MA, et al. RO 23-9424, a new cephalosporin 3'-quinolone: in-vitro antimicrobial activity and tentative disc diffusion interpretive criteria. J Antimicrob Chemother. 1993;31(1):81-88. [Content Brief]
- [2]. Christenson JG, et al. Pharmacokinetics of Ro 23-9424, a dual-action cephalosporin, in animals. Antimicrob Agents Chemother. 1990;34(10):1895-1900. [Content Brief]
- [3]. Matera G, et al. Effect of RO 23-9424, cefotaxime and fleroxacin on functions of human polymorphonuclear cells and cytokine production by human monocytes. J Antimicrob Chemother. 1996;38(5):799-807. [Content Brief]
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