1166398-85-1
Chemical Structure
Radamide
- CAS. Nr.: 1166398-85-1
- Formula:C18H18ClNO8
- Molecular Weight:411.79
IUPAC Name: ethyl 3-chloro-2-(2-((2,5-dihydroxy-4-methoxyphenyl)amino)-2-oxoethyl)-4,6-dihydroxybenzoate
InChIKey: RULSXWFZXUOCOD-UHFFFAOYSA-N
SMILES: O=C(C1=C(CC(NC2=C(O)C=C(OC)C(O)=C2)=O)C(Cl)=C(O)C=C1O)OCC
Biological Activity: Radamide is an inhibitor of Grp94 with anti-migratory activity. Radamide is used to inhibit Grp94-related diseases such as glaucoma, cancer metastasis, and multiple myeloma. Radamide exhibits selective inhibitory activity by acting on the specific structure of Grp94. Radamide derivatives show better potency and selectivity in improved structure-activity relationship studies[1].
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Radamide | Radamide is an inhibitor of Grp94 with anti-migratory activity. Radamide is used to inhibit Grp94-related diseases such as glaucoma, cancer metastasis, and multiple myeloma. Radamide exhibits selective inhibitory activity by acting on the specific structure of Grp94. Radamide derivatives show better potency and selectivity in improved structure-activity relationship studies. | |||||||||||||||||||||
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Keywords
