1177279-49-0
Chemical Structure
Nebracetam hydrochloride
Synonym(s): WEB 1881 FU hydrochloride
- CAS No.: 1177279-49-0
- Formula:C12H17ClN2O
- Molecular Weight:240.73
IUPAC Name: 4-(aminomethyl)-1-benzylpyrrolidin-2-one hydrochloride
InChIKey: KUXPUFAJKYNPMO-UHFFFAOYSA-N
SMILES: O=C1N(CC2=CC=CC=C2)CC(CN)C1.[H]Cl
Biological Activity: Nebracetam (WEB 1881 FU) hydrochloride is an orally active M1 muscarinic receptor agonist. Nebracetam hydrochloride can induce an increase in intracellular Ca2+ concentration, with an EC50 value of 1.59 mM. Nebracetam hydrochloride exhibits neuroprotective activity and the ability to improve cognitive impairment. Nebracetam hydrochloride can be used in the research of neurological diseases such as Alzheimer's disease[1][2].
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Nebracetam hydrochloride | 99.0% | Nebracetam (WEB 1881 FU) hydrochloride is an orally active M1 muscarinic receptor agonist. Nebracetam hydrochloride can induce an increase in intracellular Ca2+ concentration, with an EC50 value of 1.59 mM. Nebracetam hydrochloride exhibits neuroprotective activity and the ability to improve cognitive impairment. Nebracetam hydrochloride can be used in the research of neurological diseases such as Alzheimer's disease. | ||||||||||||||||||||
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- [1]. Kitamura Y, et al. Effects of nebracetam (WEB 1881 FU), a novel nootropic, as a M1-muscarinic agonist. Jpn J Pharmacol. 1991 Jan;55(1):177-80. [Content Brief]
- [2]. Iwasaki K, et al. Effect of nebracetam on the disruption of spatial cognition in rats. Jpn J Pharmacol. 1992 Feb;58(2):117-26. [Content Brief]
Keywords
