1185033-84-4
1185033-84-4
Chemical Structure
Keto Pioglitazone-d4 (M-III-d4)
- CAS No.: 1185033-84-4
- Formula:C19H14D4N2O4S
- Molecular Weight:374.45
IUPAC Name: 5-(4-(2-(5-acetylpyridin-2-yl)ethoxy-1,1,2,2-d4)benzyl)thiazolidine-2,4-dione
InChIKey: JMLKLMFMQRAJNI-LZMSFWOYSA-N
SMILES: C(C1C(=O)NC(=O)S1)C2=CC=C(OC(C(C3=CC=C(C(C)=O)C=N3)([2H])[2H])([2H])[2H])C=C2
Biological Activity: Keto Pioglitazone-d4 (M-III-d4) is the deuterium labeled Keto Pioglitazone (M-III)[1].
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Keto Pioglitazone-d4 (M-III-d4) | Keto Pioglitazone-d4 (M-III-d4) is the deuterium labeled Keto Pioglitazone (M-III). | |||||||||||||||||||||
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Ketopioglitazone-d4 | Ketopioglitazone-d4 is deuterium labeled Ketopioglitazone. | |||||||||||||||||||||
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Ketopioglitazone | Pioglitazone ketone is an active metabolite of the PPARγ agonist Pioglitazone (HY-13956). Formation of pioglitazone ketone occurs primarly through cytochrome P450 (CYP) isoform CYP2C8-mediated metabolism of pioglitazone. Pioglitazone ketone (100 mg/kg in the diet) reduces blood glucose levels in a KKAy mouse model of type 2 diabetes. | |||||||||||||||||||||
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References
