1185144-74-4
1185144-74-4
Chemical Structure
Olmesartan-d6
Synonym(s): RNH-6270-d6
- CAS No.: 1185144-74-4
- Formula:C24H20D6N6O3
- Molecular Weight:452.54
IUPAC Name: 1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl-1,1,1,3,3,3-d6)-2-propyl-1H-imidazole-5-carboxylic acid
InChIKey: VTRAEEWXHOVJFV-XERRXZQWSA-N
SMILES: OC(C(N1CC2=CC=C(C3=C(C4=NN=NN4)C=CC=C3)C=C2)=C(N=C1CCC)C(C([2H])([2H])[2H])(O)C([2H])([2H])[2H])=O
Biological Activity: Olmesartan-d6 (RNH-6270-d6) is the deuterium labeled Olmesartan. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Olmesartan-d6 | 99.26% | Olmesartan-d6 (RNH-6270-d6) is the deuterium labeled Olmesartan. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure. | ||||||||||||||||||||
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Olmesartan (Standard) | ≥98% | Olmesartan (Standard) is the analytical standard of Olmesartan. This product is intended for research and analytical applications. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure. | ||||||||||||||||||||
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Olmesartan-d4 | 98.83% | Olmesartan-d4 (RNH-6270-d4) is the deuterium labeled Olmesartan (HY-17004). Olmesartan is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure. | ||||||||||||||||||||
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Olmesartan | 99.91% | Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist used to treat high blood pressure. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Yanagihara H, et al. Effects of telmisartan and olmesartan on insulin sensitivity and renal function in spontaneously hypertensive rats fed a high fat diet. J Pharmacol Sci. 2016 Jul;131(3):190-7. [Content Brief]
