1216839-31-4
1216839-31-4
Chemical Structure
Indole-2-carboxylic acid-13C
- CAS No.: 1216839-31-4
- Formula:C813CH7NO2
- Molecular Weight:162.15
IUPAC Name: 1H-indole-2-carboxylic-13C acid
InChIKey: HCUARRIEZVDMPT-QBZHADDCSA-N
SMILES: O=[13C](O)C1=CC2=CC=CC=C2N1
Biological Activity: Indole-2-carboxylic acid-13C is the 13C-labeled Indole-2-carboxylic acid. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Indole-2-carboxylic acid-13C | Indole-2-carboxylic acid-13C is the 13C-labeled Indole-2-carboxylic acid. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current. | |||||||||||||||||||||
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Indole-2-carboxylic acid (Standard) | 99.78% | Indole-2-carboxylic acid (Standard) is the analytical standard of Indole-2-carboxylic acid. This product is intended for research and analytical applications. Indole-2-carboxylic acid is a strong inhibitor of lipid peroxidation. Indole-2-carboxylic acid (I2CA) specifically and competitively inhibits the potentiation by glycine of NMDA-gated current. | ||||||||||||||||||||
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Indole-2-carboxylic acid | 99.92% | Indole-2-carboxylic acid (I2CA) is a competitive antagonist of the glycine site of the NMDA receptor (Ki=15 μM, 5-fluoro-I2CA) and an inhibitor of HIV-1 integrase. Indole-2-carboxylic acid is selective for the glycine site of the NMDA receptor and blocks the enhancement of NMDA receptor by competitively inhibiting the binding of glycine to the NMDA receptor. Indole-2-carboxylic acid can also inhibit the strand transfer activity of HIV-1 integrase by chelating Mg2+ at the active site of integrase and interacting with the hydrophobic cavity. Indole-2-carboxylic acid can be used in the study of neurological diseases (such as stroke, epilepsy) and HIV-1 infection. | ||||||||||||||||||||
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References
