1262832-74-5
1262832-74-5
Chemical Structure
PF-00956980
- CAS No.: 1262832-74-5
- Formula:C18H26N6O
- Molecular Weight:342.44
IUPAC Name: ((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)(pyrrolidin-1-yl)methanone
InChIKey: RONMOMUOZGIDET-HIFRSBDPSA-N
SMILES: O=C(N1C[C@H](N(C)C2=C3C(NC=C3)=NC=N2)[C@H](C)CC1)N4CCCC4
Biological Activity: PF-00956980 is a reversible pan-JAK inhibitor with IC50 values of 2.2, 23.1 and 59.9 μM for JAK1, JAK2 and JAK3, respectively. PF-00956980 can be used in the research of lung and skin inflammatory diseases[1].
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PF-00956980 | PF-00956980 is a reversible pan-JAK inhibitor with IC50 values of 2.2, 23.1 and 59.9 μM for JAK1, JAK2 and JAK3, respectively. PF-00956980 can be used in the research of lung and skin inflammatory diseases. | |||||||||||||||||||||
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References
Keywords
