1263871-36-8
1263871-36-8
Chemical Structure
BMS-932481
- CAS No.: 1263871-36-8
- Formula:C24H24FN7O
- Molecular Weight:445.49
IUPAC Name: (S)-7-(4-fluorophenyl)-N2-(3-methoxy-4-(3-methyl-1H-1,2,4-triazol-1-yl)phenyl)-N4-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-2,4-diamine
InChIKey: NDVMOVOEROCRIO-SFHVURJKSA-N
SMILES: CNC1=C(CC[C@H]2C3=CC=C(F)C=C3)C2=NC(NC4=CC=C(N5N=C(C)N=C5)C(OC)=C4)=N1
Biological Activity: BMS-932481 is an orally active modulator for γ-secretase, selectively reduce Aβ1-42 and Aβ1-40 production, with IC50s of 6.6 and 25.3 nM, respectively[1].
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BMS-932481 | BMS-932481 is an orally active modulator for γ-secretase, selectively reduce Aβ1-42 and Aβ1-40 production, with IC50s of 6.6 and 25.3 nM, respectively. | |||||||||||||||||||||
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References
Keywords
