1295650-67-7
Chemical Structure
6,11,12,16-Tetrahydroxy-5,8,11,13-abitetetraen-7-one
- CAS No.: 1295650-67-7
- Formula:C20H26O5
- Molecular Weight:346.42
IUPAC Name: (4aR)-5,6,10-trihydroxy-7-(1-hydroxypropan-2-yl)-1,1,4a-trimethyl-2,3,4,4a-tetrahydrophenanthren-9(1H)-one
InChIKey: KPIDDSZEIRXHPH-AKYJZCGHSA-N
SMILES: C[C@@]12C=3C(C(=O)C(O)=C1C(C)(C)CCC2)=CC(C(CO)C)=C(O)C3O
Biological Activity: 6,11,12,16-Tetrahydroxy-5,8,11,13-abitetetraen-7-one is an abietane diterpenoid with antimicrobial and antiparasitic activities. It exhibits IC50 values of 3.0 and 4.8 μg/mL against Plasmodium falciparum strains D6 and W2, respectively, and inhibits the growth of Leishmania donovani with an IC50 of 12 μg/mL and an IC90 of 22 μg/mL. 6,11,12,16-Tetrahydroxy-5,8,11,13-abitetetraen-7-one can be used in studies related to fungal infections, staphylococcal infections, malaria and leishmaniasis[1].
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6,11,12,16-Tetrahydroxy-5,8,11,13-abitetetraen-7-one | 6,11,12,16-Tetrahydroxy-5,8,11,13-abitetetraen-7-one is an abietane diterpenoid with antimicrobial and antiparasitic activities. It exhibits IC50 values of 3.0 and 4.8 μg/mL against Plasmodium falciparum strains D6 and W2, respectively, and inhibits the growth of Leishmania donovani with an IC50 of 12 μg/mL and an IC90 of 22 μg/mL. 6,11,12,16-Tetrahydroxy-5,8,11,13-abitetetraen-7-one can be used in studies related to fungal infections, staphylococcal infections, malaria and leishmaniasis. | |||||||||||||||||||||
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