1299417-07-4
1299417-07-4
Chemical Structure
Frevecitinib
Synonym(s): KN-002; VR-588
- CAS No.: 1299417-07-4
- Formula:C22H21N7O2
- Molecular Weight:415.45
InChIKey: ASOKEXGIQLZRHH-HNNXBMFYSA-N
SMILES: O=C1N([C@@H]2CN(CCC2)C(CC#N)=O)C3=NC(C4=C5N(C=CC=C5)N=C4)=CC=C3N1C
Biological Activity: Frevecitinib (KN-002; VR-588) is a lung-selective pan-JAKs (i.e., JAK1, JAK2, JAK3, TYK2) inhibitor. Frevecitinib reduces sputum eosinophil levels. Frevecitinib reduces fractional exhaled nitric oxide (FeNO) levels. Frevecitinib is used for the research of moderate-to-severe asthma[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Frevecitinib | 99.42% | Frevecitinib (KN-002; VR-588) is a lung-selective pan-JAKs (i.e., JAK1, JAK2, JAK3, TYK2) inhibitor. Frevecitinib reduces sputum eosinophil levels. Frevecitinib reduces fractional exhaled nitric oxide (FeNO) levels. Frevecitinib is used for the research of moderate-to-severe asthma. | ||||||||||||||||||||
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