1325700-11-5
1325700-11-5
Chemical Structure
Firocoxib-d4
- CAS No.: 1325700-11-5
- Formula:C17H16D4O5S
- Molecular Weight:340.43
IUPAC Name: 3-((cyclopropyl-2,2,3,3-d4)methoxy)-5,5-dimethyl-4-(4-(methylsulfonyl)phenyl)furan-2(5H)-one
InChIKey: FULAPETWGIGNMT-CQOLUAMGSA-N
SMILES: O(CC1C(C1([2H])[2H])([2H])[2H])C2=C(C(C)(C)OC2=O)C3=CC=C(S(C)(=O)=O)C=C3
Biological Activity: Firocoxib-d4 (ML 1785713-d4) is the deuterium labeled Firocoxib. Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC50 of 7.5 μM). Firocoxib has anti-inflammatory effects[1].
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Firocoxib-d4 | Firocoxib-d4 (ML 1785713-d4) is the deuterium labeled Firocoxib. Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC50 of 7.5 μM). Firocoxib has anti-inflammatory effects. | |||||||||||||||||||||
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Firocoxib (Standard) | ≥98% | Firocoxib (Standard) is the analytical standard of Firocoxib. This product is intended for research and analytical applications. Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC50 of 7.5 μM). Firocoxib has anti-inflammatory effects. | ||||||||||||||||||||
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Firocoxib | 99.54% | Firocoxib (ML 1785713) is a potent, selective and orally active COX-2 inhibitor with an IC50 of 0.13 μM. Firocoxib shows 58-fold more selective for COX-2 than COX-1 (IC50 of 7.5 μM). Firocoxib has anti-inflammatory effects. | ||||||||||||||||||||
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References
