1354782-02-7
1354782-02-7
Chemical Structure
N-6-Methyl-2-deoxyadenosine-d3
- CAS No.: 1354782-02-7
- Formula:C11H12D3N5O3
- Molecular Weight:268.29
InChIKey: DYSDOYRQWBDGQQ-BXKFBODDSA-N
SMILES: OC[C@@H]1[C@@H](O)C[C@H](N2C(N=CN=C3NC([2H])([2H])[2H])=C3N=C2)O1
Biological Activity: N-6-Methyl-2-deoxyadenosine-d3 is the deuterium labeled N-6-Methyl-2-deoxyadenosine (HY-W011725). N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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N-6-Methyl-2-deoxyadenosine-d3 | 99.94% | N-6-Methyl-2-deoxyadenosine-d3 is the deuterium labeled N-6-Methyl-2-deoxyadenosine (HY-W011725). N-6-Methyl-2-deoxyadenosine is an adenine nucleoside analogue. | ||||||||||||||||||||
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N-6-Methyl-2-deoxyadenosine | 99.83% | N-6-Methyl-2-deoxyadenosine (m6dA) is an adenine nucleoside analogue. N-6-Methyl-2-deoxyadenosine targets nuclear processes and DNA replication machineries including WER, SATB1, TFAM, Jumu, SSBP1, DNA polymerase η and phage polymerase Gp90 exo−. N-6-Methyl-2-deoxyadenosine acts as a multifunctional epigenetic regulator that modulates transcription, DNA damage response, cell cycle, transposon silencing, stress adaptation, epigenetic crosstalk, and nucleosome organization in both prokaryotes and eukaryotes. N-6-Methyl-2-deoxyadenosine regulates mitochondrial epigenetic inheritance and is required for fear extinction memory in mice. N-6-Methyl-2-deoxyadenosine exhibits dysregulated levels in cancers. N-6-Methyl-2-deoxyadenosine can be used for the research of glioblastoma, triple negative breast cancer, and conditioned fear (fear extinction impairment). | ||||||||||||||||||||
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References
