138168-48-6
138168-48-6
Chemical Structure
Tyroserleutide
- CAS No.: 138168-48-6
- Formula:C18H27N3O6
- Molecular Weight:381.42
IUPAC Name: L-tyrosyl-L-seryl-L-leucine
InChIKey: MQGGXGKQSVEQHR-KKUMJFAQSA-N
SMILES: CC(C)C[C@@H](C(O)=O)NC([C@H](CO)NC([C@@H](N)CC1=CC=C(O)C=C1)=O)=O
Biological Activity: Tyroserleutide (YSL), isolated from the degradation products of porcine spleen[1], is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo[2].
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Tyroserleutide | Tyroserleutide (YSL), isolated from the degradation products of porcine spleen, is a small molecular tripeptide which inhibits tumor growth both in vitro and in vivo. | |||||||||||||||||||||
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References
- [1]. Wang C, et al. Studies on the large scale synthesis and anti-tumor activity of YSL. Prep Biochem Biotechnol. 2003 Aug;33(3):189-95. [Content Brief]
- [2]. Liang P, et al. pH-Triggered Conformational Change of Antp-Based Drug Delivery Platform for Tumor Treatment with Combined Photothermal Therapy and Chemotherapy. Adv Healthc Mater. 2019 Aug;8(15):e1900306. [Content Brief]
Keywords
