1391385-57-1
1391385-57-1
Chemical Structure
CaV1.3 antagonist-1
- CAS No.: 1391385-57-1
- Formula:C17H19ClN2O3
- Molecular Weight:334.80
IUPAC Name: 1-(3-chlorophenethyl)-3-cyclopentylpyrimidine-2,4,6(1H,3H,5H)-trione
InChIKey: AJKSBVCOTKODMF-UHFFFAOYSA-N
SMILES: O=C1N(C2CCCC2)C(CC(N1CCC3=CC=CC(Cl)=C3)=O)=O
Biological Activity: CaV1.3 antagonist-1 is a potent and highly selective CaV1.3 L-type calcium channel (LTCC) antagonist with an IC50 of 1.7 μM. CaV1.3 antagonist-1 inhibits CaV1.3 LTCC >600-fold more potently than CaV1.2 LTCC. CaV1.3 antagonist-1, a cyclopentyl derivative, has the potential for Parkinson's disease research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
CaV1.3 antagonist-1 | 98.38% | CaV1.3 antagonist-1 is a potent and highly selective CaV1.3 L-type calcium channel (LTCC) antagonist with an IC50 of 1.7 μM. CaV1.3 antagonist-1 inhibits CaV1.3 LTCC >600-fold more potently than CaV1.2 LTCC. CaV1.3 antagonist-1, a cyclopentyl derivative, has the potential for Parkinson's disease research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
Keywords
