1393371-39-5
1393371-39-5
Chemical Structure
MHY908
- CAS No.: 1393371-39-5
- Formula:C17H14ClNO3S
- Molecular Weight:347.82
IUPAC Name: 2-(4-(5-chlorobenzo[d]thiazol-2-yl)phenoxy)-2-methylpropanoic acid
InChIKey: HJOJVKDSEPDKSE-UHFFFAOYSA-N
SMILES: CC(OC1=CC=C(C=C1)C2=NC3=CC(Cl)=CC=C3S2)(C(O)=O)C
Biological Activity: MHY908 is a potent dual agonist of PPARα and PPARγ[1]. MHY908 also inhibits melanogenesis through inhibition of mushroom tyrosinase activity[2].
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MHY908 | MHY908 is a potent dual agonist of PPARα and PPARγ. MHY908 also inhibits melanogenesis through inhibition of mushroom tyrosinase activity. | |||||||||||||||||||||
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References
- [1]. Park MH, et al. Potent anti-diabetic effects of MHY908, a newly synthesized PPAR α/γ dual agonist in db/db mice. PLoS One. 2013 Nov 14;8(11):e78815. [Content Brief]
- [2]. Park MH, et al. Inhibition of melanogenesis by 2-[4-(5-chlorobenzo[d]thiazol-2-yl)phenoxy]-2-methylpropanoic acid (MHY908). Arch Pharm Res. 2015 Apr;38(4):505-11. [Content Brief]
Keywords
