1422533-70-7
1422533-70-7
Chemical Structure
LSD1-IN-49
- CAS No.: 1422533-70-7
- Formula:C26H26N2O
- Molecular Weight:382.50
InChIKey: OIBXNKRQIHNPEZ-LOSJGSFVSA-N
SMILES: O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC(C=C3)=CC=C3[C@H](C4)[C@@H]4NCC5CC5
Biological Activity: LSD1-IN-49 is an irreversible LSD1/KDM1A inhibitor with an IC50 of 29 nM against hLSD1. LSD1-IN-49 irreversibly inhibits the enzymatic activity of LSD1 by forming an adduct with flavin adenine dinucleotide (FAD) in the binding pocket of LSD1. LSD1-IN-49 is applicable to research related to schizophrenia, autism spectrum disorder and Huntington's disease[1].
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LSD1-IN-49 | LSD1-IN-49 is an irreversible LSD1/KDM1A inhibitor with an IC50 of 29 nM against hLSD1. LSD1-IN-49 irreversibly inhibits the enzymatic activity of LSD1 by forming an adduct with flavin adenine dinucleotide (FAD) in the binding pocket of LSD1. LSD1-IN-49 is applicable to research related to schizophrenia, autism spectrum disorder and Huntington's disease. | |||||||||||||||||||||
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References
Keywords
