1448009-94-6
1448009-94-6
Chemical Structure
CS1
- CAS 番号: 1448009-94-6
- Formula:C16H12O3
- Molecular Weight:252.26
IUPAC Name: 4-(6-hydroxynaphthalen-2-yl)benzene-1,2-diol
InChIKey: LDFFDYWHCCDSBO-UHFFFAOYSA-N
SMILES: OC1=CC=C(C2=CC=C3C=C(O)C=CC3=C2)C=C1O
Biological Activity: CS1 is a potent DNA Topo II α inhibitor. CS1 displays broad-spectrum in vitro antitumor effects, low toxicity in vivo and potential anti-multidrug resistance capabilities. CS1 leads to DNA damage, cell cycle arrest at G2/M phase and apoptosis[1].
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CS1 | CS1 is a potent DNA Topo II α inhibitor. CS1 displays broad-spectrum in vitro antitumor effects, low toxicity in vivo and potential anti-multidrug resistance capabilities. CS1 leads to DNA damage, cell cycle arrest at G2/M phase and apoptosis. | |||||||||||||||||||||
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References
Keywords
