1448435-17-3
Chemical Structure
Cefditoren Pivoxil hydrochloride
Synonym(s): Cefditoren pivoxyl hydrochloride; Cefditoren pivaloyloxymethyl ester hydrochloride; ME 1207 hydrochloride
- CAS No.: 1448435-17-3
- Formula:C25H29ClN6O7S3
- Molecular Weight:657.18
InChIKey: YIEBNMHIQSRKSH-OXHZFCJQSA-N
SMILES: CC(C)(C)C(OCOC(C1=C(/C=C\C2=C(N=CS2)C)CS[C@@]([C@@H]3NC(/C(C4=CSC(N)=N4)=N\OC)=O)([H])N1C3=O)=O)=O.Cl
Biological Activity: Cefditoren Pivoxil (ME 1207) hydrochloride is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections[1][2].
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Cefditoren Pivoxil hydrochloride | Cefditoren Pivoxil (ME 1207) hydrochloride is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren Pivoxil has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren Pivoxil can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections. | |||||||||||||||||||||
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- [1]. Wellington K, et al. Cefditoren pivoxil: a review of its use in the treatment of bacterial infections. Drugs. 2004;64(22):2597-618. [Content Brief]
- [2]. Cafini F, et al. Enhanced in vivo activity of cefditoren in pre-immunized mice against penicillin-resistant S. pneumoniae (serotypes 6B, 19F and 23F) in a sepsis model. PLoS One. 2010 Aug 10;5(8):e12041. [Content Brief]
Keywords