144887-95-6
Chemical Structure
SK609
- CAS No.: 144887-95-6
- Formula:C10H14ClN
- Molecular Weight:183.68
IUPAC Name: 4-(2-chlorophenyl)butan-2-amine
InChIKey: JPYONMJJWKTSBP-UHFFFAOYSA-N
SMILES: ClC1=C(CCC(C)N)C=CC=C1
Biological Activity: SK609 is a selective dopamine D3 receptor agonist with activity that improves dopamine and norepinephrine levels in the cerebral cortex. SK609 has been successfully used to suppress dyskinesias in Parkinson's disease models and alleviated muscle twitches induced by L-dopa. SK609 improved performance in sustained attention tasks by significantly reducing misses and false alarms. SK609 may provide an inhibitory option for suppressing movement and cognitive impairment in patients with Parkinson's disease[1].
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SK609 | SK609 is a selective dopamine D3 receptor agonist with activity that improves dopamine and norepinephrine levels in the cerebral cortex. SK609 has been successfully used to suppress dyskinesias in Parkinson's disease models and alleviated muscle twitches induced by L-dopa. SK609 improved performance in sustained attention tasks by significantly reducing misses and false alarms. SK609 may provide an inhibitory option for suppressing movement and cognitive impairment in patients with Parkinson's disease. | |||||||||||||||||||||
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Keywords
