1572051-31-0
1572051-31-0
Chemical Structure
O-7460
- CAS No.: 1572051-31-0
- Formula:C25H48FO5P
- Molecular Weight:478.62
IUPAC Name: 1-((fluoro(methyl)phosphoryl)oxy)-3-isopropoxypropan-2-yl oleate
InChIKey: ZLEFMXNNQCABDB-SEYXRHQNSA-N
SMILES: CC(OCC(COP(F)(C)=O)OC(CCCCCCC/C=C\CCCCCCCC)=O)C
Biological Activity: O-7460 is a potent and selective DAGLα inhibitor, with an IC50 of 0.69 μM. O-7460 shows selectivity over onoacylglycerol lipase (MAGL), human CB1 and CB2 cannabinoid receptors. O-7460 can decrease HFD-caused an up-regulation of 2-AG levels[1].
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O-7460 | 95.0% | O-7460 is a potent and selective DAGLα inhibitor, with an IC50 of 0.69 μM. O-7460 shows selectivity over onoacylglycerol lipase (MAGL), human CB1 and CB2 cannabinoid receptors. O-7460 can decrease HFD-caused an up-regulation of 2-AG levels. | ||||||||||||||||||||
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References
Keywords
