1619903-54-6

LY2857785 Chemical Structure
1619903-54-6

Chemical Structure

LY2857785

  • CAS No.: 1619903-54-6
  • Formula:C26H36N6O
  • Molecular Weight:448.60

IUPAC Name: (1r,4r)-N1-(4-(3-isopropyl-2-methyl-2H-indazol-5-yl)pyrimidin-2-yl)-N4-(tetrahydro-2H-pyran-4-yl)cyclohexane-1,4-diamine

InChIKey: LHIUZPIDLZYPRL-MXVIHJGJSA-N

SMILES: CC(C1=C2C=C(C3=NC(N[C@H]4CC[C@H](NC5CCOCC5)CC4)=NC=C3)C=CC2=NN1C)C

Biological Activity: LY2857785 is a type I reversible and competitive ATP kinase inhibitor against CDK9 (IC50 11 nM) and other transcription kinases CDK8 (IC50 16 nM), and CDK7 (IC50 246 nM).

Cat. No. Product Name Purity Description Pricing
HY-12293 		LY2857785 99.21% LY2857785 is a type I reversible and competitive ATP kinase inhibitor against CDK9 (IC50 11 nM) and other transcription kinases CDK8 (IC50 16 nM), and CDK7 (IC50 246 nM).
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