168828-60-2
168828-60-2
Chemical Structure
PNU-101603
- CAS No.: 168828-60-2
- Formula:C16H20FN3O4S
- Molecular Weight:369.41
IUPAC Name: (S)-N-((3-(3-fluoro-4-(1-oxidothiomorpholino)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
InChIKey: WNRIDZUNMXATND-ZDUSSCGKSA-N
SMILES: CC(NC[C@H]1CN(C2=CC=C(N3CCS(CC3)=O)C(F)=C2)C(O1)=O)=O
Biological Activity: PNU-101603 is a sulfoxide metabolite of Sutezolid (HY-10392). PNU-101603 alone or combined with SQ109 (HY-14989) shows excellent activity against Mycobacterium tuberculosis (MTB), as well as against agent-susceptible and multidrug-resistant TB[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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PNU-101603 | 98.82% | PNU-101603 is a sulfoxide metabolite of Sutezolid (HY-10392). PNU-101603 alone or combined with SQ109 (HY-14989) shows excellent activity against Mycobacterium tuberculosis (MTB), as well as against agent-susceptible and multidrug-resistant TB. | ||||||||||||||||||||
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References
- [1]. Reddy VM, et al. SQ109 and PNU-100480 interact to kill Mycobacterium tuberculosis in vitro. J Antimicrob Chemother. 2012 May;67(5):1163-6. [Content Brief]
- [2]. Barbachyn MR, et al. Identification of a novel oxazolidinone (U-100480) with potent antimycobacterial activity. J Med Chem. 1996 Feb 2;39(3):680-5. [Content Brief]
Keywords
