1800576-41-3
1800576-41-3
Chemical Structure
NJK14047
- CAS No.: 1800576-41-3
- Formula:C27H27NO5
- Molecular Weight:445.51
IUPAC Name: N-cyclopropyl-4'-(4-(2,3-dihydroxypropoxy)benzoyl)-6-methyl-[1,1'-biphenyl]-3-carboxamide
InChIKey: ZQIUCYZGBDPMLG-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C2=CC=C(C(C3=CC=C(OCC(O)CO)C=C3)=O)C=C2)=C(C)C=C1)NC4CC4
Biological Activity: NJK14047 inhibits p38 MAPK and the differentation of naive T-cells to Th1 and Th17 cells. NJK14047 ameliorates the collage-induced rheumatoid arthritis and Imiquimod (HY-B0180)-induced psoriasis in mice[1].
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NJK14047 | NJK14047 inhibits p38 MAPK and the differentation of naive T-cells to Th1 and Th17 cells. NJK14047 ameliorates the collage-induced rheumatoid arthritis and Imiquimod (HY-B0180)-induced psoriasis in mice. | |||||||||||||||||||||
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References
Keywords
